THE PROTEIN DATABANK (PDB)

INTRODUCTION

      The Protein Data Bank (PDB) was created at Brookhaven National Laboratories (BNL) (1) in 1971 as an achieve for biological macromolecular crystal structures. In the beginning the achive had seven structures, and with a handful annually more were deposited. In the 1980s the number of deposited structures began to rise dramatically. This was due to the developed technology for all elements of the crustallographic process, the add-on of structures influenced by nuclear magnetic resonance (NMR) methods, and changes in the community views about data sharing.

      In October 1998, the management of the PDB became the responsibility of the Research Collaboratory for Structural Bioinformatics (RCSB). In general, the goal of the RCSB is to establish a reference based on the most sophisticated technology that alleviate the use and analysis of structural data and hence creates a resource for the research of biology.

The printscreen of The Protein Data Bank (PDB) website.

http://www.rcsb.org/pdb/explore/explore.do?structureId=3Q6R

Here we attached some molecules that is deposited in the Protein Data Bank (PDB)

Molecule Name	LIPASE
Classification	LIPASE
Brookhaven code	1GT6
Number of chains	6
Number of groups	538(171)
Number of atoms	4140(209)
Number of bonds	4280

Molecule Name	NEPRILYSIN
Classification	HYDROLASE
Brookhaven code	1R1H
Number of chains	2
Number of groups	696(300)
Number of atoms	5595(367)
Number of bonds	5787

Molecule Name	PROBABLE PROTEASE HTPX HOMOLO
Classification	HYDROLASE
Brookhaven code	3CQB
Number of chains	6
Number of groups	190(217)
Number of atoms	1429(343)
Number of bonds	1619

Molecule Name	ATP-DEPENDENT PROTEASE LA 1
Classification	HYDROLASE
Brookhaven code	3M65
Number of chains	4
Number of groups	408(36)
Number of atoms	3290(36)
Number of bonds	3336

Molecule Name	CYCLOPHILIN
Classification	ISOMERASE(PEPTIDYL-PROLYL CIS-TRANS)
Brookhaven code	1CLH
Number of chains	-
Number of groups	166
Number of atoms	2535
Number of bonds	2607

Molecule Name	CAPSID PROTEIN
Classification	VIRAL PROTEIN
Brookhaven code	3Q6R
Number of chains	6
Number of groups	620(990)
Number of atoms	4826(1067)
Number of bonds	5087

CONCLUSION

      We are thankful as we were blessed with this opportunity to learn this Protein Data Bank (PDB). Even though we are not major in this biological course, but we are so excited to know this application of RasWin which can portray the structural  molecular.